New frames, Casipian and others are made slightly oversized to allow you to create a tight slide to frame fit. So yes, with a combination of filing, stoning, and lapping you can fit the frame to the slide. The problem is that when it binds, it's not all that easy to figure out where its binding, and its way too easy to remove too much metal from the wrong place. You will still be able to create a gun that goes bang, but unless you remove the right amount of metal from the right places you won't have that tight fit you may have been looking for.
Unless you plan to do this a number of times and want to learn the process, I'd buy a fitted frame and slide.
Oh, and by the way, the only reason your caught up with reloading is that your not shooting enough!