One thing I will tell you about coyotes..contrary to what many say, they are tough animals..Elmer Keith figured they were one of our toughest animals to kill in the U. S. They have taken some hard hits and still move a aways..so when you want them dead right now on the spot, you are asking alot...I have had excellent success with the .22-250 at ranges out to 600 plus, but for really long stuff, I like a bit more caliber and bullet wt. but in some states that is not a pratical plan..I dont want you to think they are armor plated, but this winter I shot at a coyote in the edge of a pasture, the distance was maybe 250 yards, the hold looked good there was no wind, and when I squeezed off, he just whirled and ran into the swamp....I had been in there and tracking wasn't much of an option due to the water that covered the area....So I chalked it down to a miss, but I have checked that area every couple days since that shot, no coyote..Usually, if I miss he will be back, wary, and running at the first indication I am in the area, but I will see him...with all the calving going on in the area, I am sure he would have returned...nothing...I think I hit him and he got off in to the heavy stuff, and water...so just keep that in mind....they are a wonderful game animal....