Mike: Natchez Shooters Supply just sent out a flier advertizing 380 ammo, among others, for about $20 per box of 50.
And reloading is more than just a viable option. If you are capable of properly handling a firearm and practicing adequate safety measures without incident you should not have to worry about your abilities to reload.
Personally reloaded ammo is more than adequate for personal defense and may well be of higher quality than something you get in a box from a factory in Mexico. Think about reloaded ammo being custom tailored to you, your shooting style and defensive needs, and that you can practice with what you carry.
I would not wait and see about the future availablility of ammunition, I would make my own. There are any number of sources for brass, bullets, powder and primers and I would get started by looking into reloading. There is a cost efficiency to reloading that should make any American taxpayer happy and you will have all the ammo you want.
The 380 is a very easy cartridge to load for, as long as you keep your thumb out of the way (lolol). You don't have to go whole hog at first; there is a hand held loading tool that looks like a large set of pliers that allows you to reload in singular stages (size, prime, etc., I think Lee makes it, but reloading for the 380 is something you should really consider. jmtcw.