ThesilverSlayer - I have thought about this subject and your situation for a few days now - it has bothered me. I know I have given you the wrong impression in my zeal about my feelings and how I think you should think. That is not going to happen, I can not or should I force the way I feel about reloading onto someone else. For that, I apologize. Steve P is correct. More than likely you will not experience any problems as far as safety is concerned as long as you are using low pressure loads and as long as you can get the spent primer out of the case, it will go bang, safely. I answer these type questions with my type thinking in place, but not everyone thinks like I do. I think that one well placed shot is important and should be my goal. I have many single shot guns, so it goes along with my thinking. I do not own a semi-auto of any kind in center fire. Even with "plinking" loads, I try to load and shoot as if every shot is important. I use quality components and take extra care when reloading. I really do enjoy the reloading experience. I have a single stage press and more than likely will not own a progressive. So with this type thinking, I recommend using brass that is of at least middle quality, which I consider the Remington and Winchester type of brands. When you get off center primer holes, it indicates poor quality to me. If you have off center primer holes, how much does the case capacity vary, how many reloads will you get out of this brass? To many folks this does not matter, they saved a few bucks. It does matter to me. I load under the assumption that if it is worth doing, it is worth doing right, as repeatable as possible, as accurately as possible with safety in mind. Again not everyone feels this way. My thinking includes using brass of known origin, preferably new. I do not full length size new brass, so that I have one less brass working, shortening the life of the case. I do clean primer pockets for every round, even plinking rounds, I clean my brass after every firing, not to mention using run out gauges to monitor bullet seating. I consider the first loading a fire forming load in bottle necked cases and do not resize, unless I have to. I keep my brass sorted and in lots for each gun. Some folks pick up their brass from the range. I am not saying they do not give a rats a** about safety or accuracy, because they do care - they put saving money ahead of that concern. Every time someone says they use range brass, the bottom line is they saved money. They do not mention it is safer, more accurate or easier, because it isn't. To me it is worth spending a little more. I look for more than, will it go bang, with out blowing up in my face? So the bottom line is, yes the once fired PMC brass with off center holes will more than likely work with low pressure loads and as long as they are low pressure, safe. How long the brass will last, and what kind of accuracy you will get, I can not answer. If these factors are not important to you, then you are home, buddy. Good Shooting and Good Luck