I only know one person who owns a NAA .22, but I do not know the model. We used to have an outdoor range here in our county, but it was closed down a few years ago. The closest target distance was 7.5 yards and he could not hit the paper with it at that distance. Beyond 3 feet it was pretty useless. He has other guns and is a pretty good shot. It ain't the shooter.
Enough people are killed with .22s each year to prove they can work if you're able to hit a vital organ. It's hard enough to do with any gun if the perp is moving, you're excited, furniture in the way, etc., etc., etc. You might not have the opportunity to stick it up to someone's head, or close enough to hit him with the NAA. My wife has a LCP and I have a 638 as well as backup guns. I'm sticking with those as the very bottom line in self-defense. And I don't see this new Ranger as a plinker, either. On the other hand, I know some people will love it, and I hope they sell a gazillion of them. I want to see all firearm companies do well (except Taurus). So even though I see no use for this gun -- I'm glad someone will.