How many of you actually have hunted in Grizzly country? I know a few here have as well as myself.
Let me tell you, you don't think about toting that rifle everywhere with you. When in camp sometimes it is something you forget to grab when you are doing stuff around camp. When I was hunting in Alaska, we slept in tents in the middle of nowhere, I had my handgun on my side 24/7. I slept with it in my sleeping bag. A rifle in a tent when your sleeping will do you no good. A handgun with you in your sleeping bag, can be deployed very fast.
I think we all would agree a rifle is your best tool, and is the more powerful than the most handgun rounds. But a handgun can and has been used to kill Grizzly.
While in Alaska, we had a Grizzly come into our camp. We spotted it a long distance away working a mountain ridge, within 2 hours it worked toward our camp. We were in a low area by a lake, and when the bear crossed the river it went out of sight, we back out of came and went to higher ground, so we could see where the bear was going to come in at. The bear came in by the lake, and was less than 50 yards from our tents. We were 200 yards on the other side of camp watching the bear. The bear spotted us and stood up on it hind legs to look around, and decided to get out of the area. Had we not spotted the bear and it decided to take the higher ground and approach our camp, it would of been only 25 feet from the camp and we would not of seen it until it was right on top of us.
Long story short, take what you think will work. Having 2 guns is better than one! Use your head in Grizzly country, and always be aware of everything around you.