I bounced a .45 PRB off a deer at a little over 125 yds with 70gr 3F. Found it in the mud looking for blood, hair marks on one side, patch marks on the other. Those little balls loose energy fast. I read somewhere that it takes 700 Ft. Lbs. energy to kill a deer (maybe in the Hawken/Seneca manual), and with that load you are pretty close to that at 100 yds. After that day, I switched to maxi balls for hunting. I also bounced a PRB off of a 1/2" plate hinged "turkey head" at 75yds, at a Thanksgiving shoot with 60gr Pyro. Hit it right at the bottom at the hinge. They gave me the turkey, and repainted the target. Is a 127gr .45 PRB a deer killer? Yes, in the right hands....