Yeah, if you ever see an original Glock 10mm or .45acp upper for sale, snap it up, because they are as rare as hen's teeth.
Glock used to sell complete uppers for a very reasonable price, but stopped about 5 or 6 years ago.
The Lone Wolf slide, barrel, and parts will set you back around $450, plus you'll have to look at that silly wolf etched into the slide and barrel.
If you get the Glock 21, all you need is a 10mm conversion barrel and mags.
At the range yesterday I had a couple failures to feed with my 21, what in the world I thought, oops, I had loaded .45 ammo into my 10mm magazines.