I replaced a Sig P250 with the PX4 and am very happy with it...I have big hands and the large grip module fits me fine. I like the ease of disassembly, the feel and functioning to date has been flawless... The only downside that I have found with my Storm is that the rear sight needs to be drifted to shoot to point of aim and I am afraid to hit it too hard with a punch.. it shoots about two inches left @ 15 yds... not a big problem for a defensive handgun... I found a Fobus holster that fit it and am satisfied with my carry rig..
I could not get used to the Sig's DOA trigger... the Beretta's trigger was very good and crisp... I liked the Beretta enough that I just bought a "little brother" for the .45 and got a U22 Neos...
Hope this helps,
Themoose