What does your bore slug at? Ideally your throats and bore will be the same. Usually, .001 to .002 over throat / bore diameter results in best accuracy and least leading when using cast bullets. If you use a fairly soft bullet .002 over you should get good accuracy with minimal leading provided your barrel is not way under or oversize. Hard cast can work great, but they have to be used in guns with matching throat / barrel diameters, otherwise you will get gas cutting and subsequent leading. A slightly oversize soft bullet will, under pressure, "slug up" to form a good fit, with minimal leading, though they may lead some at max velocities if you are loading to "Ruger only" specs. Some guns do better with a gas check bullet at high velocities. If your throats are significantly over bore diameter, there is not much you can do (a problem I have with one of my Colt .45 SA's). If they are significantly tighter then the bore, the the cure is easy, just have them opened to match the bore.
Larry