moons ago in my formative years (12 years old) with no real direction in BP hunting i used a big maxi ball (385gr buffalo bullet) with a 90gr charge of Goex or Pyrodex. it shot really well out of my .50 Renegade- but....
the numerous instances of memory loss from the recoil made me begin to wonder why i was shooting a massive chunk of lead at a 150lb whitetail at distances of less than 30 yards.
i then began to experiment at the farm on dead steers and heifers with different possibilities. i had scoffed at the idea of the original loadings as archaic and outdated. i was wrong. really wrong. i was shocked at the efficiency of a .50 round pill with loadings as low as 50gr of powder. it was faster to load, less mess and a heckuva lot easier on my shoulder and cheek.
i have shot alot of things with the Hornady Great Plains bullet (deer, hogs and one elk). it's devastating. 90gr of black powder produced on my most accurate loadings in 30 years of shooting BP rifles. i have a target saved from 1987 that has five .50 holes in a space not much larger than a quarter from 40-45 yards. literally one jagged hole.
you will know when the charge is ignited, that is for sure.