I try for shoulder, sort of, a little low - if angling away ideal is aim for off shoulder (going through lungs on the way).
This last Monday I shot a 9 pointer in the evening... and for the first time ever, I took a head shot. The deer was about 50 yards when I saw him, directly behind my tree... by the time I turned around that way he was moving into thick stuff, about to disappear... I grunted, he stopped w/large tree obscuring chest/neck... looked right at me, and I got a solid sight picture and shot him between the eyes. Unlike most of my deer which run off 40 yards or so, he went four feet, straight down. See below (after being boned out). Bullet hit between eyes, ended up in neck; recovered the core (30-30, 150gr Federal)