If you put the slug through both lungs, honestly, the deer will die quick. And yes, I agree most self defense ammo works fine for deer IF you wait for a broad side AND have good marksmanship. I used the .38 Spl 158 gr LHP(BB load 20C) Standard pressure through the shoulder(which is just lean muscle, not bone) and the deer ran 30' ish yards and folded up dead. A shoulder shot is not a standard of "bone crushing" loads and to measure their strength. If you have dogs, cats, etc. put your finger in the center of thier "shoulder" if you call it that. Front, high, and low is somewhat bone, nothing strong though. The majority of the flesh in the middle..... ain't nothing but simple lean muscle which is what ammo of all kinds was made for. Anyone that thinks that a deer's shoulder has this massive "Bone" to penetrate through then please do an Anatomy Check..... As Mikey said, please keep it peaceful. We are here to compare notes, and that's all. A shoulder shot with hogs may mean something, but a shoulder shot on a whitetail....... nope.