There are times my fingers/hands go numb. I think it's carpo tunnel for me. Been welding and grinding for 15+ years, plus hanging on to a Harley for 30 years of riding. When I am in the habit, I would take the Glucosamine Chondroitin and it seemed to help. My hips and knees are bothering me more now than ever. My problem is, I have a few days where I feel pretty good, and I'll get out of the habit of taking it. Then I'll have days were I push it,like today, gonna fire up the log splitter, and everything is back to hurting. Gonna take some right now, before I even get started. gypsyman