Don't know what caliber your considering but the 2 I have owned, 22hornet & 223 preferred light bullets. The hornet shot 45gr great but the 223 groups opened up with even 55 grain. It preferred the 45gr white box Winchester loads.
My 223 was a 1-14 twist I never checked the hornet but assume it was the same. If you want to shoot heavier bullets then there are better choices, but if you can be happy with the lighter bullets the 527s are wonderful guns.
Oh one other thing the mini masseur action is not very smooth when it's new. But lots of cycling helps it immensely.
Regards,