Tough question. LR is .222. .22 Mag??? .224? As far as forcing the larger bullet and jacketed thru the barrel, probably no noticeable effect unless you are shooting high level match... Then, too sloppy. At the same time, there is a discussion among barrel makers, the long rifle shoots lead bullets while the mag has a jacketed bullets. Simply put, the makers don't spend extra on steel for jacketed bullets with the long rifle family and its lead bullets... You go to a jacket bullet and rifling does not last as long. Had a smith tell me he had seen shout out micro groove barrels... Marlin/Mossberg. And in the days of the "new" Hornet, silly people would shoot the new ammo in the .22 WCF rifles (same case, lead bullet, black powder) and had a smooth bore in no time... Yes, you can. Should you? Your pocket book. Luck.