I have had two 41 Mag Contender barrels, a 10" and a 14". I used IMR 4227 and 110 in mine with 240 gr XTP's. Neither of my barrels shot worth a toot with the 4227, but turned in impressive groups with 110.
Never figured this out since my 41 revolver and rifle both shoot better with 4227. Guess each gun has its own likes and dislikes. I just always disliked the blast and flash with 110 even though you do get more velocity.
I am getting two 41 mag carbine barrels next week, one for a Contender and one for an Encore. I hope they like the 4227 even though the flash and blast is not near as bad from a carbine barrel.