i have a 77 allweather in 280.i have used it on coyotes.your choice of bullet is going to decide wether or not you got enough fur left to make one mitten or two.lol.some guys don't like to put big holes in the fur,me i could care less.use 139 grn hornady spire points over a hot charge of 4350.our coyotes here in ny get up to 40 lbs or more.i have killed one that weighed 45,actual weight on registered scales.average size is 30 lbs.i liked the way the 280 performed only reason i stopped using it was the noise.during the middle of the night that report will carry a long ways.didn't need the extra attention.i would have people at the general store the next morning asking me what i had killed .great flat shooting deer cartridge with a little heavier bullet.good luck with it.