From my experience, obviously the incapacitation power from the 223 is the bullets velocity and the phonomenon called hydrostatic shock. Reducing the velocity in the 223 may cause you to have an ineffective hunting round for medium game. If I was going to hunt with a suppressed firearm, I would go with (at least)30 caliber, subsonic, and 180 grain. The penetration and inertia for bullet upset would still be present; you would have a reliable hunting round, and enjoy the benefit of a suppressed round in the form of a subsonic round. My 2 cents.