I guess I opened up a real can of worms here.
Here is the main reason why I asked my original question:
I have a Ruger Super Redhawk chambered in .454 and when I fire my heavy sided 45 Colt loads through it with cast 255g SWC, I end up with some very decent accuracy. I have tested three powders in the .454 ammo using 325g RNFP GC's, 250g XTP's and 240g XTP Mags. The 325 grain bullets place about five inches high and to the left by comparison to the 45 Colt ammo. The 250 XTP's place very nice groups about 1 to 2 inches high at 25 yards and the 240's place nice groups right dead on with the 45 Colts at 25 yards.
If you exprapolate the deviation out to 100 yards, an inch high at 25 yards could be 4 inches high at 100 yards, assuming all things are constant over the longer distance. So, I'd rather use the 240 grain bullet in the case I would like to interchange ammo in the revolver and not have to worry about adjusting the sights every time I change ammo, or forgetting to adjust the sights, etc. (I think you get the idea)
I target shoot, plink, and rarely get the chance to shoot prairie dogs once a year so it's not as if I'm going out and hunting large game or dangerous game where it would be well worth the added expense of buying "top notch" and relatively expensive bullets. I'm toying around here! Do I need 1880 fps? HECK NO! OK, yes, it's a lot of fun to shoot loads like that but what I'm really after is something to do a bit more than my 45 Colt loads and place in the same general area on a target as the 45 Colt loads as well. Since I'm basicaly plinkiing and target shooting, I don't really need the extra expense of the bullets and if lightening up the velocity is all I need to do in order to use standard XTP bullets, then that's what I'll do. Typically what I do with other calibers that are somewhat expensive (45-70, 38-55, etc) is I move to cast bullets instead of paying high prices for the jacketed counterparts. It appears, however, that I'll need a lighter bullet than the 325 grain bullet I have tested in order to stay within POI with my 45 Colt loads.
So basically, I'm just trying to see if I can save a few $$$, but if it's gonna cost me the revolver, my hand and more to do that, then it's certainly not worth trying to cut corners.
Any advice with regard to this is much appreciated but I think I already know my answer; either pay the price or just shoot 45 Colts from the revolver and leave it at that.