Hi Mike,
I found that the 180gr .40 XTP from T/C and the 200gr .40 XTP from Hornady shoot really well in my 45 with 120gr 777. The Hornady 200XTP took 2 deer this year and was absolutely devastating. No complaints. Many people like the lighter bullets for the higher velocities, but the heavier 180 & 200 have better ballistics and great penetration. From all of the threads I have read over the last 6 months, it seems to me that the majority of 45 shooters get much better accuracy with loose powder that with the pellets. Good luck!