I think (key word think) most people with common sense have some provisions at home or even a retreat. But the op was load out . Could he mean the place you have decided to make your stand has become useless , lost or becomming too dangerous to stay ?
If so what would you carry out with you ? I would guess it would be the bug out bag . The grab and run bag. Of all the things that would influnce your choice of contents experince would be the leader. If you have ever experinced living in such a situation then you would know first hand what you need to get by. If you have no experince then you either need to seek out someone who has it or get some.
what experince ?
walking with a load , how far can you walk ? how much weight can you carry ? combine the two .
what is in walking distance that would offer shelter ? help ? or other things you will need.
how much food can you live off of ? can you ration ?
water , can you provide yourself with water ? filter ? where to find it ?
protection , weapon and ammo . Size , amount of ammo , can you hide it ? can you access it ? can you carry the weight ?
clothes what do you really need ? cold ? warm ? wet ?
just a few things to consider if you really have to grab and run . In reality you don't need to pack a load of equipment you can't carry far. What you might do is if possible spend a night out in the woods or back yard during each season of the year. Take a hike with a small load maybe lunch and a few other items . See how far you can go in relative comfort . See how much food you need to pack just a light load.
Read some survival books but also read stories of people who lived thru. bad times . Read books about hunting and war in Africa. The Civil war and other wars around the world where resupply was non existant. I read a book that had a story about one of the great hunters who was a scout and spy during the first world war in Africa and others in WW2. In one chapter they listed what they carried. It was quite lite and they stayed out long periods of time. Ammo was under 200 rounds. Food was stuff like a loaf of some bread and some meat maybe a little rice or beans. A cup to cook in nothing heavy. If you have to walk away from all your supplies or they are destoryed before you get home you will need to have a plan B. What happens if say you are ingreat health and can carry 45 lbs . You walk until your food is gone what next ? Did you plan to be in an area that you could aquire more food ? or did you strike out on a journey with out direction ? Could you have rationed and had the food last longer ? could you have watched your food and aquired more before yo ran out ? I think many will be dropping items that when packing a load out figured they could not do with out only to find they could not carry it.
I ramble sorry.
A list . water, and a way to filter it and carry it , food (as much as you can tote) and a way to eat it. clothes as needed ( the clothes you wear still add weight to your load), knife , fire starter ( bic lighters are lite and work) ( cotton and vasilene work well) . A cup like canteen cups , tarp ( a couple military ponchos work well) . Weapon and ammo, Soap. and tolet paper, medicine and first aid , para cord works in so many applications, I always like to have fishing line ( can strip out one thread from para cord if needed ), hooks , float and sinkers along with some berkley bait sealed in a zip lock bag. By now the load is about all I want to carry any distance. You might add sunscreen , salt peper , hot sauce or other comfort items . Dice might be nice to play with for a break and they are lite.
Oh well my 2 cent worth , sure others will pick it apart
buit then they may point out something I missed I may need ! I hope it's lite