I have a similar problem--I'm thinking that once I use up my can of unique, and my 2 cans of accurate #2, I'm going to try to just use Bullseye--I load for .380, 9mm, .45 acp, .38 special , and .357 mag. I don't know if the bullseye will work all that well in the .357, but it hasn't done too bad in the other calibers for me from time to time. That IMR 4227 sounds interesting, I may have to check it out, perhaps ever buy some to give it a try.
cybin