My experience with both on deer is that both kill equally well. The 150 grain blows through but expends less of its energy than the 130, but both are plenty effective. I use the 130 more often because it is more than adequate for Texas whitetails and hogs, and the recoil is just a tad less. There is a velocity difference, and this results in a slight difference in trajectory that is all but unnoticeable under 300 yards. I have never shot that far at a deer, so I consider it academic. However, you might find it important, so I thought I'd mention it.
