I am a Remington 700 man through and through, though I do own one Ruger. It is a 375 Ruger Alaskan with the matte stainless finish, and wears a Leupold 1.5-5x20 scope. It loves Hornady 270 grain bullets and RL15. It has killed 2 elk to date, one bang flop at 100 yds, and the other was shot quartering away at 376. That farther one made it about 90 yds before giving up. No problems with this rifle at all.
As far as the 264 winnie is concerned I agree it is a way underrated cartridge. I am on my second one, both of them being on Mauser 98's. The one I have now my great grandfather built in the 70's on a VZ 24 action. Very accurate rifle, but the magazine is a little short, so with the long 6.5 bullets I have to seat them in a lot farther than I would like. It doesn't get hunted much its mostly a safe queen, though some day I will take it for a walk and kill a deer with it. Just because.
The first 264 i had did such a good job killing deer and elk with a 140 speer grandslam, that my best friend became obsessed with them. He now has two Model 700's in 264, an interarms in 264, and two 260 remingtons. And there has been talk of adding a 6.5-06.