The wife and I have friends in Southern Indiana and we are planning a visit there during deer season next year or the year after that. Having taken a look at your deer regs, it is obvious that I don't own the "ideal" gun. Here us what I do own that might work:
1) Scoped Ruger Security Six in .357 - I would say that I am good to about 50 yards with it.
2) Smooth Bore 20ga NEF with Red Dot sight. Shoots slugs into a 3" group at 50 yards and about a 5" group at 75 yards.
3) A NEF 45/70 barrel that I could shoot shortened case rounds in to comply with the regs.
A forth option would be to pick up a .357 barrel for the Handi - but if any of the above would work, I will forgo the expense
Any feedback from Indiana hunters would be appreciated!