I've used them years past; 338 winmag, .340 Weatherby, .338 RUM. All with Barnes 185 XLC to 210 XBT (this was pre TSX) and killed elk/Aoudad sheep around 250 with 185XLC and 180 Accubond with the 338 win/RUM. I've killed plains game with 210XBT from both a 338 winmag and .340W out to 375 or so. All killers. I can highly recommend it.
I never tried the 160 X but I would if I still had a 338. I use a .35 Whelen Ackley Improved in place of any 300 mag or 338 mag. I can do this as I use the Banres 200X or TTSX going 2950 from my rifle, plus, it's an old friend, and very jealous rifle-it "demands" to go hunting all the time! ha. A 300 RUM is awesome, lots more range than a 338, add a 338 mag to it and you have a perfect combo for world class hunting. I highly recommend Barnes TSX/Partitions & Accubonds/Hornady/Sierra bullets, in that order. Good luck to you. Merry Christmas.