Depending on where you live, breeding season for mink begins about the end of February and can last til early April. The females are in heat for about 3 weeks during this time. Furs prime about mid October so do your trapping from this time til mid February. Don't continue to trap through the breeding season and in many areas, the seasons prohibit trapping beyond Feb 15th or 28th anyway. You can target males or females as in many populations, the males tend to wander farther from the dens than the females do.