My particular load is 13.6gr of 2400 and the XTP 158 gr HP.My grandson has killed 3 deer to date with it, and at 60-75 yards had clean pass throughs on all 3 deer, all medium sized does. If shots are chosen judiciously there will be no problem. I would say that broadside shots on typical deer at under 100 yards should work just fine. Quartering shots, longer range, or an exceptional animal, could make it dicey. That is a moderate load, it just happens to be the most accurate in my barrel, and I was more concerned with that than power, and the results proved it to be quite adequate.