Generally speaking, I like South Carolina: there are some nice people there, plus they have a long deer season with generous bag limits. On the other hand... their forebearers were stoopid, starting the war between the states. And nowadays SC is overrun by 'Conservative Christians' which are tied together by only a couple things... they don't like abortion, they don't like gay people, and they're sure God is on their side (just like the Jihadists). They're also infected with that strange combination of Christianity and jingoistic nationalism... they like the US being everywhere, and confuse 'defense' expenditures with patriotism. In other words, they're not given to careful consideration of anything outside their little circles.
So... for Ron Paul not to win SC kind of makes sense, esp. as he didn't do much campaigning there, relative to the others.