Spruce hits the nail on the head in both his posts. It DEPENDS on the pistol, the grip, single action, double action, length of pull, breaking trigger weight release and so on.
I just got an SA XDM in .40 cal. It has the adjustable backstrap. The smallest backstrap felt the best in my hand, but at the range my trigger finger was to close. Thus I was forcing the squeeze and pulling my shots to the left, ALL THE TIME.
Finally I benched the gun and realized it shot great. But off hand it was me. Solution change the back strap, wider grip, less finger on the trigger, more even pull.
PAH