I have a few...
My three Rugers 4 5/8, 5.5 and 7.5" will do 2"+ at 50 and 6" at 100. I have another 7.5" Bisley that I "tuned up" that will do about 2" at l00. All with open sites.
My Colt New Forntier will do a about 4" at 100 and another '50s SSA with a 5.5 is good for 6" at 50, again with open sites
I have a couple Italian Colt copies 4 1/2 and 5.5" barrels that are never fired at 100 but will hit a cabbage or mellon at 50 yards.
All three of my Marlin rifles have open sites, My LTD has buck horns, my std 1894 a rec peep and my Cowboy tang peep. ALL will keep shots on a base ball at 100 with out too much trouble.
My lil H&R BC barrel will do one hole at 50 and under 2" at 100 and my 454 re chambered 45 Colt again one ragged hole at 50 and just over 1" at 100 all with my hand loads. Both these wear good scopes.
Even my 10" Contender will do 2" at 100. It wears a 2X Leupold.
Told ya I had a few 45's...
CW