I can say that I have never progressively (or otherwise) reloaded hand gun cases for purely "accurate" reasons. I want every one of them to go BANG on demand, shoot EXTREMELY WELL at belly distance (just over arm's length), and VERY GOOD across a room. If I can "waste" a man-sized silhouette at 5 yards (say 5-inch or less group)...I'm calling that good (not saying that a 5-inch group is the best I can do). Can I wring greater accuracy out - probably. Do I need to? So far, I am saying "no."
45 ACP loadings are (have to get from load book at house later this evening and post):
X.X grains of IMR 700X, CCI X00 primer (LR), under 185 grain cast HP's
X.X grains of IMR 700X, CCI X00 primer (LR), under 2XX grain cast RN's