Four years ago my high school buddy and I drove the wife's Mazda RX-8 up the Alcan. We were in no hurry and spent 8 days making the drive. We spent three days at a festival in some small town off the road, where they were having an auto show.
There was wildlife all over the road. Foxes, Coyotes, and Wolves ran across the road in front of us. Stone Sheep, Dall Sheep, Caribou, Moose, and Bison were all standing in the road. We had to stop and wait for them to get out of the road. Watch out for those Wood Bison, they are much bigger than the Bison in the lower 48. They are often lying on the side of the road, and they don't move for nobody. They would have no trouble turning your car or truck over.
If you are serious about driving the highway, go to you local book store and purchase a book called the "Alaska Milepost". That book give all the information needed for traveling the highway. All points for gasoline, or diesel. All lodging and food locations. Points of interest such as places to fish, hike, or viewing. There are camping areas ran by the Provences, all along the way and they are listed in the Milepost. All kinds of things are explained in there such as getting a three day fishing permit, history of the small towns and communities, hot springs, and side trips such as going to Dawson City, then driving the Top Of The World Highway, from Dawson City over to the Taylor Highway in Alaska. The "Milepost" also tells about all the cities and towns in Alaska as well as Canada. It give the same information for traveling around Alaska as well as Canada.
Good Luck, Rog