Mike, I think this has been a very good discussion & no one has been arguing, each has just given their own experiences. I mentioned earlier that I'd taken 4 elk with my Ruger 45's but didn't give loads, etc. On 3 of them I used a 325 gr LBT slug using a 22 grs of H110, all 3 bullets exited & were one shot kills. The other was with my old 260 gr Keith over 24 grs of H110 (mag primers) this was also a one shot kill at 168 yds, complete pnetration. I love my 45's & they might be a better caliber but I just have a "thing" for my 44's.
I've taken 5 elk with them over the years, mostly using the old Keith #429421, 250 gr cast, always getting complete penetration using 21 grs of 2400, never did care for Elmer's load of 22 grs for some reason, although I have taken some game with it including my last bear.
I've also taken 2 elk with the 41 maggie, one with a 230 gr Keith & the other with a 250 gr LBT, same results, complete penetration & one shot kills. The strange thing about these 11 kills is, the fastest 2 came with the 41 maggie. Two kills isn't enough to really form an opinion, just telling it the way it happened. All 3 work, I'll pick my 44's first, but thats just me.
Dick