I never bothered to reload for the 38 spl., as I used to get all my practice ammo for free from the PD. It consisted of 2.8 grains Bullseye under a HB Wadcutter. Nice, accurate, pleasant load. When reloading for a revolver, its important to not go below the minimum recommended load in a loading manual. To light a powder charge, and you risk sticking a bullet in the barrel. If this happens, and you are firing fast double action, you risk bulging your barrel, or worse... Not as big a deal in a semi auto as usually an underpowered load that sticks a bullet will not have enough power to cycle the action and allow you to send another round down range.
There is a long running debate about "detonation" (a gun exploding because of too little powder in the shell casing). Personally, I do not believe it, and have never seen conclusive evidence of it happening, and I have looked... I believe most so called instances of detonation can be traced back to using the wrong powder, double charges, plugged bore, etc..
Larry