I have a 6x 45 or 6/223 which is almost the same as a 6 TCU but 2460 didn't work for me. The gun is capable of the one hole groups but accuracy just wasn't there versus other powders. I've used it with great success in a 223 with 62gr bullets though out of a 1"7" twist HBAR. The powder I use in the 6x 45 is H4895. I get the highest velocity and best accuracy from it. But if you already have it, I'd certainly try it. May work exceptionally good in yours. The bullet weights I shoot in the 6x 45 are 70gr TNT, 80gr Remington HP, and Speer 90Gr sp.