Times like this make me glad I have popular, but not trendy, calibers. I've still been able to get my .44 mag, .45acp (but not as reliably as the other calibers I'm listing), .243, and such, but it seems every time a box of .22lr hits a shelf, people flock to the counter to claim it.
Fortunately, I keep a decent stock of ammo in most of my calibers, excepting the .44, which has me planning to start reloading. Big margin with that round, and I could pay for a decent Lee kit within four or five boxes.