My favorite load with my Guide Gun is 52gr of IMR3031, Remington 405gr JSP, WLR primers, Rem NP brass(1700fps cold, 1810fps hot). However I'm in the process of searching for my new "favorite" using H322, as it is much less temperature sensitive.
My current favorite cast load is 46gr of H322, 405gr flat point, plain base, 3 lube groove, 18bhn, .460" diameter, WLR primers, Rem NP brass, for 1770fps.
I've heard that the Cowbody barrels are better than the Guide Gun, in that Marlin doesn't screw them up so bad stamping nomenclature and broach-cutting dovetails. With that said, you might be able to get good results with .459" diameter cast bullets.