Most of the time Ive found I run out of elevation for the longer shots when an opportunity to play at some distance arises (ie, more up adjustment for on out there) so by starting out with the rear setting down more toward the lowest end to establish -0- I can get more out of whatever adjustment the sight has for elevation.
Rarely have I had not enough adjustment to go lower if I started at about 1/4 up from the lowest setting and picked a front height to get on center at, say 50yd., which would be about the closest Id need to be. That stills gives me some latitude in charge/velo and bullet weight for up close too.
Just consider this as an option for the type of shooting you think you want to do, I only know that it works for me
, YMMV.