I've done it before when I had a 2506. It's going to depend on your particular rifle if the necks will need to be turned. I'd suggest running the brass thru the die, trim it to length, seat a bullet and gently chamber the round. If it mets resistance just before you lock the bolt (assuming a bolt rifle), you probably need to turn the necks. The Remmy I had didn't require neck turning. If it does need neck turning, I'd suggest doing it like a TNT chamber and take a thousandth off at a time. The first piece of brass is a pain but after that all you have to do is run them thru the neck turning tool. Neck turning like a TNT rifle means more potential accuracy. You can also make the brass from 270 if you have that available as well.
As I reread your post, you have nickel brass. That may give you some issues. You'll need to try it but generally nickel brass is more brittle and you may have split necks. That's a maybe, you'll have to try it to know. Make sure to use a good lube and lube the inside of the neck.