Being a "gun nut", I tend to buy, sell, and trade quite a bit, often because I like a particular firearm, with the caliber being secondary. As a result, I do have a large selection of calibers. I am set up to reload about 15 or so, and have components for all. That said, I have my favorites, and most used. For me, its the .22rf, 22-250, .223, 204 Ruger, 358 win., 35 whelen, 308 and 30-06. 44 mag and 45 acp in pistol. Each caliber serves a particular function in the type of shooting I do, or is the chambering of a particular gun type I like.
Larry