I shoot a lot. I'm a meat hunter. Hogs have been high on my list as they have historically been numerous in my neighborhood, affording me A LOT of trigger time. I went annually to South Carolina for deer meat, until their legislature started 4X price gouging non-resident license and tag fees (compared to residents) - sorry SOB's.
In almost 30-years of reloading ammunition and shooting bullets at game, I have tried a plethora of ammunition combinations, striving for the "most accurate", but foremost, the combination that will produce humane DRT shots. "They don't take it well in the neck", as my SCDNR Host has told me all these years.
To understand my thinking that the "most accurate" combination is not the end all when hunting game, is in part to understand my hunting neighborhood, which is a thick jungle of saw palmetto, sable palm, oak hammock, and riverine swampland with long (up to 275 yards) and narrow (12-feet) shooting lanes affording about 5 seconds of seeing, reacting, and shooting prior to losing sight of the game. If game is hit and does not immediately fall, it could well be "Game Over Man" for recovery, as crawling in the swamp on hands and knees behind a flashlight searching for a wounded hog at O'Dark-30 in 85 degree F and 95 percent humidity weather is a recipe for human disaster. Waiting to recover until morning and daylight assures loss of the meat in these conditions.
I tried bullets by Federal, Winchester, Speer, Hornady, Sierra, and Nosler. I found the Nosler Ballistic Tip bullet to be the most accurate on paper targets. I won't shoot it at game anymore as the off side fist sized hole is ghastly (by comparison).
Speer Grand Slam (GS) bullets are just plain expensive, fair to good accuracy, and penetrate like only one other I have tried. I have not tried the evolutionary offerings in solids or strictly copper. I won't use GS's again as they impart practically none of their energy while passing through as a pencil thin hole (as an FMJ might).
Winchester, Federal, Hornady, and Sierra make exposed lead tipped hunting bullets that rapidly expand on impact. These too are accurate (to a degree) on paper targets. Though not the most accurate, I would have been "OK" to have selected one of these and stopped looking. I would have been mistaken if I had.
I shot the Nosler Partition at paper and though not quite as accurate as the Ballistic Tip, it compared well with the others, and on game for my conditions, I found in the Partition the BEST hunting bullet. Accolades include accurate, penetrating (through and through), pencil thin in, pencil thin out, NEVER recovered one in game, very high energy shedding, and humane results. To say I have taken hundreds of animals using Partitions, each with a single shot, would be an understatement. Partitions lay them on the ground, many DRT, provided I do my part and put the bullet where it does its work the best. I always use a rock sold rest and (prefer to) shoot them in the neck.
I've hunted "enough" (but am not through) to overcome any jitters, to control breathing and trigger management, to refuse a rushed or marginal shot, to know that this is only one of many animals in the woods - another will be along, and to enjoy the experience. I am comfortable and confident in my equipment, my handloads, my stands, and my methods. That's my $0.02.