Well, I don't have any health issues that would prevent me from carrying an automatic, or a revolver.
I do however, have 1st hand experience in being in a fight with either.
I'll say that the revolver did a better job in my first disagreement, and a year later another disagreement (this time with TWO Dallas boys) my automatic left me wondering why I got rid of my wheel gun, so I went and got another wheel gun
I've owned and carried lots of auto pistols, but I have far more trust in a well tuned Smith 357 magnum.
That Ruger SP-101 wouldn't scare me if somebody handed me one to fight with. As long as it was loaded with 38 Special, or 357 mag.
I'd be concerned if it was any 9mm.
I'm a Smith guy, and I carry one every day.