Thanks for all the replies guys, I really appreciate it.
To answer a few questions posed, I do not plan on doing any precision (long range) shooting...although it is certainly within my interests, it is not an immediate goal or need for this hunt.
But, on the same token, I believe in being very prepared for anything that I do in life, and this hunt will be no different. I spoke with the guide yesterday and he said most shots will indeed be under 200 yards but they like hunters to be prepared for out to 300 yards...ultimately whatever your comfort level is (some are comfortable out to 300 yards+).
I made it clear that I would be staying within my reasonable limits (which I currently do not know, since this will be my first high powered rifle hunt). I do quite a bit of gun hunting here in NJ, but HP rifles are not permitted for deer, so I hunt with a shotgun and muzzleloader.
I am comfortable with my scoped T/C High Plains Sporter (rare side hammer ML model) out to 100-125 yards, placing near touching groups, so I don't think a HP rifle will be a problem out to 200 yards. But, there are conditions over longer ranges that I need to be aware of, learn, practice, etc. That's why I'm starting early now, plenty of time before November!
As far as bullets, it seems the most common answer is to shoot whatever shoots well out of your gun, afterall shot placement is the most important element of killing an animal quickly.
There is some confusion on my part regarding the softer, ballistic tip style bullets versus more middle grade/harder bullets (NPs, Bearclaws, Core-Lokts, etc)...and I'm not sure which is better.
From what I've researched, discussed, and read...ballistic tips expand rapidly and often don't leave much of an exit hole (if any) but do an incredible amount of damage internally. The only problem I've heard about is when animals are BIG, these bullets expand TOO quickly and dont gain enough effective penetration.
The question I have is, is that a moot point for mule deer and whitetails?
Apparently many hunters have had great success with ballistic tips, but others (whether out of preference, confidence, or otherwise) prefer the medium grade and harder bullets to ensure more than adequate penetration and a high percentage chance of an exit wound.
In the end, I just don't want to make a bad decision that will not result in a quick kill on an animal. The shot placement is in my hands, but I need to be clear on a quality bullet (off the shelf loads, since I don't reload) suited for Wester Mulies and Western/Eastern Whitetails at both short and longer ranges (0-300 yards).
I hate to beat a dead horse here, but I think most of that has been answered and I can be confident in either a ballistic tip or a medium grade bullet. Both will kill just as effectively.
If anyone has any additional thoughts, please let me know. And thanks again for all the feedback!