Hey varmit_master, From what little amount that I have worked with them. Nosler is a little (note a little) more accruate. To myself the V-Max will blow a bigger hole. The transfer of energy is unreal. I mannly shoot varmits with a 270 110grV-max 48.5 gr Varget. its about 3175+/- fps 100yd groups 1 3/4 to 2 1/4" When it's a hit WE TALKING BIG RED HALO!!!