Wow a 450 pistol, want to talk about recoil, I would think it would be murder, unless you shot reduced loads,even at that it would be more than a 454 Casull. The 450 or 45/70 holds almost twice the amount of powder and can slug much bigger bullets with good accuracy, I did reload a Hornady 300gr jhp's for my guidegun, I was surprised how the start load was very moderate 1600fps, till it got up near the max load 1900, then the recoil was in there;) I guess you better take a good hold, or you will be eating that pistol;) To me anything that can hold more than 40gr of powder belongs in a rifle, Just my thoughts. Aim small hit small. RAMbo.