k fellers, let me tell yu jus how tuff the local yotes are here in mo. last deer season i shot one at bout 200 yrds with 06 125 grn handload doing near or better than 3000fps, perfect shot, right in crease behind shoulder perfectly middle of body up and down wise. knoncked him flatter than a pancake. dint think much of it, 10 min later i looked up and he was trottin roun like nuttin ever happened, big red spot on him exactly where i aimed! i watched him trot aroun for a few more min thru my 4x12 bsa scope. he dint even look like he had a bellyache or a hangnail. finally he was sniffin roun and turned towards me at bout 180yrds, he got same load center of chest. that one did it for him, never even exited. when i looked at him, first shot left a 3 finger gash on exit with chunks of lung hangin out but he never even acted like he knew it. moral of this story? 2 days later, shot one in same place with 243 100 grain factory load. ded dog immediate. lol figger that out! oh 22 mag mite be good for head shots and lung shots if yu dont mind trackin a little but give me a 243 anyday!