I'll also agree with 44mans recomendation, try LOTS of different brands. I recently purchased a S&W model 41, and found that you do need to try lots of different brands of ammo. The difference in different brands is dramatic, even amoung target ammo. You should make a point to try some of the target grades of ammo, not just the cheap stuff. This should be done using some sort of a rest to get the best possible accuracy. Once you find one that shoots extremely well you will at least have a benchmark for your guns accuracy. I find my 41 likes CCI green tag the best, however it is about $8.50 a box of 100. I found CCI standard velocity and Winchester T22 target ammo, shoot the best of the less expensive brands of ammo. The dynapoints are the best of the bargain brands for me. But it seems the cheaper I go, the more the groups open up. For most practice and general plinking I use either the standard velocity or the T22, and when I'm in the mood to really try to drive tacks, I buy a box of Green tag.