If you are loading after a shot without cleaning, you need to make sure the bullet is seated into or below the fouling ring in the barrel. If loading subsequent load after load, the fouling ring can progress further from the breech and ultimately be too far from the powder and have disatrous results. If you wipe after every shot, not to worry. I shoot T7 and seat the bullet/sabot with pretty much the same pressure each time, that being real firm, without having any accuracy problems. Whatever you do, just be consistent load to load.